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The Mechanism and Cytoplasmic Control of Mammalian Protein Synthesis

AbstractMy aim in this article is to summarise the state of knowledge, as I see it, concerning a number of selected topics in the field of mammalian protein biosynthesis, and to discuss the major...

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The Cytoplasmic Control of Protein Synthesis

AbstractAfter a long period during which to claim to be studying translational control was to invite a variety of negative responses from sympathetic looks to undisguised sneers, it has now become such...

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Leptospirosis

AbstractLeptospirosis is no longer considered merely an occupational disease among workers in wet environments contaminated with rat urine. Many wild and domesticated animals harbor the organism and...

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Internal initiation of translation of picornavirus RNAs

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Health and the built environment

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Malignant Triton Tumor Presenting as a Rectal Mass in an 11-Month-Old

AbstractWe report the case of an 11-month-old white male who had a family history of neurofibromatosis, had multiple café-au-lait spots on the trunk and extremities, and was diagnosed with a malignant...

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Healthy Places Research: Emerging Opportunities

Key PointsEmpirical research provides a solid foundation for designing and building healthy places. Such research has not always been used in the design professions.Research performed to date can guide...

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Making Healthy Places

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Chernobyl and Iodine Deficiency in the Russian Federation: An Environmental...

AbstractThe Chernobyl nuclear disaster of April 26, 1986, triggered a chain of devastating events that later included an unexpected increase in childhood thyroid cancer and evidence of iodine...

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Nd:YAG laser therapy for rectal and vaginal venous malformations

AbstractBackgroundLimited therapeutic options exist for rectal and vaginal venous malformations (VM). We describe our center’s experience using Nd:YAG laser for targeted ablation of abnormal veins to...

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Sternocostal slipping rib syndrome

AbstractPurposeClassical slipping rib syndrome (SRS) can be subclassified based on anatomical location. We describe our experience with three patients suffering from symptomatic sternocostal slipping...

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Magnetic cryogels as a shape-selective and customizable platform for...

AbstractCryogels consisting of polyvinyl alcohol and iron (II, III) oxide magnetic nanoparticles coated with a model drug—acetaminophen, were developed as a tunable platform for thermally triggered...

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Picornaviruses break the rules

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Initiation without an end

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Cinderella factors have a ball

Translation of messenger RNA into a protein requires recognition of the precise starting point on the mRNA. In eukaryotes that is accomplished by scanning of the small ribosomal subunit along the RNA....

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The mechanism of eukaryotic translation initiation and principles of its...

Key PointsTranslation is a cyclical process in which ribosomal subunits that participate in initiation are derived by recycling of post-termination ribosomal complexes (post-TCs) that have completed...

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Learning is good, but not enough: Comment on the article “Child-focused...

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